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Wainwright Sales Agreement [Member] H.C. Wainwright Sales Agreement [Member] H.C. Wainwright Sales Agreement [Member] H.C. Wainwright Sales Amended Agreement [Member] H.C. Wainwright Sales Amended Agreement [Member] H.C. 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Specified Period Maximum beneficial ownership allowable per agreement (percent) Registration Rights Agreement, Maximum Beneficial Ownership Allowable For Counterparty Registration Rights Agreement, Maximum Beneficial Ownership Allowable For Counterparty Maximum number of shares authorized per agreement (in shares) Sale Of Stock, Maximum Number Of Shares Authorized Per Agreement Sale Of Stock, Maximum Number Of Shares Authorized Per Agreement Commission on gross proceeds due to third party (percent) Sale Of Stock, Commission On Gross Proceeds Due To Third Party Upon, Percent Sale Of Stock, Commission On Gross Proceeds Due To Third Party Upon, Percent Stock issued (shares) Stock Issued During Period, Shares, New Issues Proceeds from issuance of stock Proceeds from Issuance of Common Stock Document and Entity Information [Abstract] Document and Entity Information [Abstract] Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Shell Company Entity Shell Company Entity Current Reporting Status Entity Current Reporting Status Document Type Document Type Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Amendment Flag Amendment Flag Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Accrued Liabilities [Abstract] Schedule of Accrued Liabilities Schedule of Accrued Liabilities [Table Text Block] Debt Securities, Available-for-sale [Abstract] Amortized Cost Debt Securities, Available-for-sale, Amortized Cost, Fiscal Year Maturity [Abstract] Less than one year Debt Securities, Available-for-sale, Maturity, Remainder of Fiscal Year, Amortized Cost Greater than one year Debt Securities, 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loss Operating Income (Loss) Other income (expense): Nonoperating Income (Expense) [Abstract] Investment income, net Other Nonoperating Income (Expense) Interest expense Interest Expense Total other income (expense), net Nonoperating Income (Expense) Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Less - net income (loss) attributable to noncontrolling interests Income (Loss) from Continuing Operations, Net of Tax, Attributable to Noncontrolling Interest Net (loss) income attributable to Caladrius Biosciences, Inc. common stockholders Net Income (Loss) Available to Common Stockholders, Basic Basic and diluted loss per share Earnings Per Share, Basic and Diluted, Other Disclosures [Abstract] Caladrius Biosciences, Inc. common stockholders (in usd per share) Earnings Per Share, Basic and Diluted Weighted average common shares outstanding Weighted Average Number of Shares Outstanding, Diluted [Abstract] Basic and diluted shares Weighted Average Number 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Operating Lease, Right-of-Use Asset Weighted average remaining lease term for operating leases (in years) Operating Lease, Weighted Average Remaining Lease Term Weighted average discount rate for operating leases (percent) Operating Lease, Weighted Average Discount Rate, Percent Statement of Stockholders' Equity [Abstract] Statement [Table] Statement [Table] Statement, Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Total Caladrius Biosciences, Inc. Stockholders' Equity Parent [Member] Series B Convertible Preferred Stock Preferred Stock [Member] Common Stock Common Stock [Member] Additional Paid in Capital Additional Paid-in Capital [Member] Accumulated Other Comprehensive Loss AOCI Attributable to Parent [Member] Accumulated Deficit Retained Earnings [Member] Treasury Stock Treasury Stock [Member] Non- Controlling Interest in Subsidiary Noncontrolling Interest [Member] Class of Stock [Axis] Class of Stock [Axis] Class of Stock [Domain] Class of Stock [Domain] Series B Convertible Preferred Stock Series B Preferred Stock [Member] Statement [Line Items] Statement [Line Items] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Beginning Balance (shares) Shares, Outstanding Beginning Balance Adoption of accounting standard New Accounting Pronouncement or Change in Accounting Principle, Effect of Adoption, Quantification Unrealized gain on marketable securities Other 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Allocation of Recognized Period Costs [Table Text Block] Schedule of Total Compensation Cost Related to Nonvested Awards Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block] Schedule of Fair Value of Share-based Compensation Awards Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Available-for-sale Securities [Table] Schedule of Available-for-sale Securities [Table] Financial Instrument [Axis] Financial Instrument [Axis] Financial Instruments [Domain] Financial Instruments [Domain] Money Market Funds [Member] Money Market Funds [Member] Corporate Debt Securities [Member] Corporate Debt Securities [Member] Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-sale [Line Items] Gross Unrealized Gains Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax Gross Unrealized Losses Debt Securities, Available-for-sale, Accumulated Gross 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[Line Items] Deferred Revenue Arrangement [Line Items] Milestone payment received on grant award Milestone Payment On Grant Award, Cash Received Milestone Payment On Grant Award, Cash Received Progress payment received on grant award Progress Payment On Grant Award, Cash Received Progress Payment On Grant Award, Cash Received Accrued grant funding Accrued Grant Funding Accrued Grant Funding Amortization of accrued grant funding to offset expense Amortization Of Accrued Grant Funding Liability To Offset Expense Amortization Of Accrued Grant Funding Liability To Offset Expense Statement of Cash Flows [Abstract] Cash flows from operating activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Share-based compensation Issuance of Stock and Warrants for Services or Claims Depreciation and 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[Abstract] Right-of-use assets Operating lease liabilities, current Operating Lease, Liability, Current Operating lease liabilities, noncurrent Operating Lease, Liability, Noncurrent Operating lease liabilities Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Total share-based compensation expense General and Administrative [Member] Selling, General and Administrative Expenses [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based compensation expense Allocated Share-based Compensation Expense Unrecognized compensation cost Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized Expected weighted-average period in years of compensation cost to be recognized Share-based Goods and Nonemployee Services Transaction, Valuation Method, Expected Term Total fair value of shares vested Adjustments to Additional Paid in Capital, Share-based Compensation, Stock Options, Requisite Service Period Recognition Weighted average estimated fair value of shares granted Salaries, employee benefits and related taxes Employee-related Liabilities Operating lease liabilities - current Retention Payable CIRM upfront funding - current Customer Advances, Current Other Other Accrued Liabilities Total accrued liabilities Accrued Liabilities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Share-Based Compensation Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Available-for-Sale-Securities Cash, Cash Equivalents, and Marketable Securities [Text Block] Preferred stock, shares authorized Preferred Stock, Shares Authorized Preferred stock, Series B convertible redeemable preferred stock liquidation value, share of common stock Convertible Preferred Stock, Shares Issued upon Conversion Preferred stock, par value (in usd per share) Preferred Stock, Par or Stated Value Per Share Preferred stock, shares designated Preferred stock, shares designated Preferred stock, shares designated Preferred stock, shares issued Preferred Stock, Shares Issued Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Common stock, par value (in usd per share) Common Stock, Par or Stated Value Per Share Common stock, shares authorized Common Stock, Shares Authorized Common stock, shares issued Common Stock, Shares, Issued Common stock, shares, outstanding Common Stock, Shares, Outstanding Treasury stock (shares) Treasury Stock, Shares Number of restricted stock issued Stock Issued During Period, Shares, Restricted Stock Award, Gross Value of restricted stock issued Stock Issued During Period, Value, Restricted Stock Award, Gross Weighted average estimated fair value of restricted stock issued Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Vesting terms (years) Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period